Concepts and Models for Drug Permeability Studies

Concepts and Models for Drug Permeability Studies

This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route. Updated information regarding the most recent in vitro models to study the permeability of drugs Short and concise chapters covering all the biological barriers with interest in drug permeability A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models Simple and clear scientific content, adaptable for young scientists and experimented researchers


Author
Publisher Woodhead Publishing
Release Date
ISBN 0081001142
Pages 408 pages
Rating 4/5 (41 users)

More Books:

Concepts and Models for Drug Permeability Studies
Language: en
Pages: 408
Authors: Bruno Sarmento
Categories: Science
Type: BOOK - Published: 2015-09-30 - Publisher: Woodhead Publishing

This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrie
Nanotechnology for Oral Drug Delivery
Language: en
Pages: 534
Authors: João Pedro Martins
Categories: Business & Economics
Type: BOOK - Published: 2020-07-30 - Publisher: Academic Press

Nanotechnology for Oral Drug Delivery: From Concept to Applications discusses the current challenges of oral drug delivery, broadly revising the different physi
Characterization of Pharmaceutical Nano- and Microsystems
Language: en
Pages: 416
Authors: Leena Peltonen
Categories: Science
Type: BOOK - Published: 2020-10-27 - Publisher: John Wiley & Sons

Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field
Drug Delivery with Targeted Nanoparticles
Language: en
Pages: 790
Authors: Yılmaz Çapan
Categories: Medical
Type: BOOK - Published: 2021-11-30 - Publisher: CRC Press

Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important a
Drug Delivery Approaches
Language: en
Pages: 528
Authors: Bret Berner
Categories: Medical
Type: BOOK - Published: 2021-07-27 - Publisher: John Wiley & Sons

Explore this comprehensive discussion of the application of physiologically- and physicochemical-based models to guide drug delivery edited by leading experts i
The Blood-Brain Barrier
Language: en
Pages: 357
Authors: Nicole Stone
Categories: Medical
Type: BOOK - Published: 2022-06-22 - Publisher: Springer Nature

This detailed volume features techniques to explore the complex interface that separates the systemic circulation from the central nervous system, known as the
Nanoparticles in Life Sciences and Biomedicine
Language: en
Pages: 552
Authors: Ana Rute Neves
Categories: Medical
Type: BOOK - Published: 2018-02-13 - Publisher: CRC Press

The creation of new and more efficient therapies for improving human health greatly depends on drug delivery systems. Nanotechnology has emerged as a powerful s
When the Shape Does Matter: Three-Dimensional In Vitro Models of Epithelial Barriers
Language: en
Pages:
Authors: Elena Martinez
Categories: Science
Type: BOOK - Published: 2021-01-18 - Publisher: Frontiers Media SA

The Theory of Endobiogeny
Language: en
Pages: 236
Authors: Kamyar M. Hedayat
Categories: Science
Type: BOOK - Published: 2019-06-18 - Publisher: Academic Press

The Theory of Endobiogeny Volume 2: Foundational Concepts for Treatments of Common Clinical Conditions addresses the core elements of the adaptation response to
A Practical Guide to Rational Drug Design
Language: en
Pages: 292
Authors: Sun Hongmao
Categories: Medical
Type: BOOK - Published: 2015-10-05 - Publisher: Woodhead Publishing

This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-w